The immune system is more enhanced with the more beta glucan you take. With a highly potent beta 1, 3-D glucan the immune system is greatly enhanced taken daily. The how much you need is determined by body weight. We suggest you take 2mg per/kg. For example, a 220 lb. person that weighs100 kilograms will need 200 mg of beta glucan (two 100 mg capsules) for an effective immune support. For maximum immune support, you take 20 mg per/kg. A 500 mg capsule will provide maximum immune support.